Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, No 20, Section 3, Ren Min Nan Lu, Chengdu, Sichuan 610041, People's Republic of China.
Biol Trace Elem Res. 2011 Oct;143(1):97-102. doi: 10.1007/s12011-010-8849-0. Epub 2010 Oct 2.
Lead poisoning is one of the most significant environmental health threats which children face. The aim of the study was to evaluate the relationship between the blood lead level (BLL) of children and environmental pollution, as well as the effect of BLL on children's heath, in the biggest city in south-west China. A questionnaire survey was administered to 3,624 children's (6 months-7 years old) guardian in urban Chengdu from 2007 to 2009, collecting data on inhabited environment, living habits, and health status. All blood samples were collected for BLL test when the children came to the hospital. The analysis was conducted in West China Second University Hospital, Chengdu, China in December, 2009. A total of 3,624 children were included. The mean BLL was 62.31 μg/L. Three hundred thirty-three (9.2%) of 3,624 children's BLL were above 100 μg/L. Taking Chinese medicinal herbs usually, puffed foods, and substitutes of breast milk were risk factors (P < 0.05).The study shows that Chinese children's lead poisoning prevention and treatment lags far behind developed countries. The findings have implications for environmental health policy.
铅中毒是儿童面临的最严重的环境健康威胁之一。本研究旨在评估中国西南部最大城市儿童的血铅水平（BLL）与环境污染之间的关系，以及 BLL 对儿童健康的影响。2007 年至 2009 年，我们对成都市城区 3624 名（6 个月至 7 岁）儿童的监护人进行了问卷调查，收集了居住环境、生活习惯和健康状况等数据。当儿童到医院就诊时，我们采集了所有血液样本进行 BLL 检测。2009 年 12 月，在中国成都华西第二医院进行了分析。共纳入 3624 名儿童。平均 BLL 为 62.31μg/L。3624 名儿童中有 333 名（9.2%）的 BLL 超过 100μg/L。经常服用中药、膨化食品和母乳替代品是危险因素（P<0.05）。本研究表明，中国儿童铅中毒的预防和治疗远远落后于发达国家。这些发现对环境卫生政策具有重要意义。
