Clinic for Hand-, Plastic- and Microsurgery Friederikenstift, Hanover, Germany.
Br J Surg. 2010 Dec;97(12):1825-30. doi: 10.1002/bjs.7257. Epub 2010 Oct 1.
The medial wall of mammalian veins is generally thin and fragile compared with the thick muscle seen in arteries. This makes venous microanastomoses time consuming and challenging. This study aimed to determine the feasibility and effectiveness of using the BioWeld(®) Tube in conjunction with a surgical glue (butyl-2-cyanoacrylate) in performing sutureless venous microanastomoses.
The feasibility and effectiveness of microvascular anastomoses in a rabbit jugular vein model were investigated in six animals, using the BioWeld(®) Tube in conjunction with butyl-2-cyanoacrylate surgical glue. Patency and tissue repair mechanisms at the anastomotic site were assessed 1 week after the procedure.
All anastomoses remained patent at 1 week. Muscle necrosis occurred only in areas where the tissue was subject to the fold-and-bond procedure.
The study showed the feasibility and short-term effectiveness of the BioWeld(®) Tube in facilitating venous anastomoses.
与动脉中厚的肌肉组织相比，哺乳动物静脉的内侧壁通常较薄且脆弱。这使得静脉显微吻合既耗时又具有挑战性。本研究旨在确定使用 BioWeld（®）管结合手术胶（丁基-2-氰基丙烯酸酯）进行无缝合静脉显微吻合的可行性和有效性。
在 6 只兔子颈静脉模型中，使用 BioWeld（®）管结合丁基-2-氰基丙烯酸酯手术胶，研究了微小血管吻合的可行性和有效性。术后 1 周，评估吻合部位的通畅性和组织修复机制。
所有吻合口在 1 周后均保持通畅。只有在组织经历折叠和粘合过程的区域才发生肌肉坏死。
该研究表明，BioWeld（®）管在促进静脉吻合方面具有可行性和短期效果。
