Inaba R, Watanabe S, Okada A, Moroji T
Department of Public Health, School of Medicine, Kanazawa University.
Nihon Eiseigaku Zasshi. 1990 Oct;45(4):904-8. doi: 10.1265/jjh.45.904.
To investigate the effects of whole-body microwave exposure on plasma corticosterone, glucose, uric acid and allantoin levels, rats weighing 245-300 g (light group) and 440-510 g (heavy group) were exposed to microwaves with a frequency of 2,450 MHz at the power density of 10 mW/cm2 under an ambient temperature of 21 to 23 degrees C for one hour. Rectal temperatures were increased by 3.4 degrees C in the light group and 1.4 degrees C in the heavy group after microwave exposure. Plasma levels of corticosterone, glucose and uric acid did not change in both groups after microwave exposure. Plasma levels of allantoin increased significantly only in the heavy group after microwave exposure. These results suggest that the plasma levels of allantoin, a metabolite of uric acid, may be useful as a biological variable for assessment of the effects of whole-body microwave exposure in rats. The increase of plasma allantoin level after microwave exposure could not be explained only by the degree of increased rectal temperature caused by hyperthermic effects of microwaves.
为研究全身微波暴露对血浆皮质酮、葡萄糖、尿酸和尿囊素水平的影响，将体重245 - 300克（轻组）和440 - 510克（重组）的大鼠，在环境温度21至23摄氏度下，以10毫瓦/平方厘米的功率密度，暴露于频率为2450兆赫的微波下1小时。微波暴露后，轻组大鼠直肠温度升高3.4摄氏度，重组大鼠升高1.4摄氏度。微波暴露后，两组大鼠血浆皮质酮、葡萄糖和尿酸水平均未改变。仅重组大鼠微波暴露后血浆尿囊素水平显著升高。这些结果表明，尿酸代谢产物尿囊素的血浆水平，可能作为评估大鼠全身微波暴露效应的生物学变量。微波暴露后血浆尿囊素水平的升高，不能仅用微波热效应引起的直肠温度升高程度来解释。
