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[墨西哥女性风疹血清流行病学。一项全国概率调查]

[The seroepidemiology of rubella in Mexican women. A national probability survey].

作者信息

Gutíerrez Trujillo G, Muñoz O, Tapia Conyer R, Bustamante Calvillo M E, Alvarez y Muñoz M T, Guiscafré Gallardo J P, Magos C, Sepúlveda J

机构信息

General de Servicios Técnicos y Proyectos Especiales, Secretaría de Salud.

出版信息

Salud Publica Mex. 1990 Nov-Dec;32(6):623-31.

PMID:2089638
Abstract

A rubella seroepidemiologic survey was carried out in a rural population to better understand the epidemiology of this infections disease in Mexico. 24,331 serum samples from women between 10 and 44 years old were collected during 1987-1988 from the 32 federal states. Samples were tested for Rubella Antibodies by use of hemagglutination inhibition with a titer 1:8 bring considered as positive; 79.96 per cent (CI 95%, 7.5-80.5%) of women were seropositive, seropositivity increased with age, from 69.26 per cent in the age group of 10 to 14 years old, to 87.84 per cent in the 40-44 age group. Seropositivity rates were lower in southern states than in northern states and, higher in urban areas that rural areas (82.4 vs 76.6%); statistical significative difference in seropositivity rates were found between girls less than 14 years of age in urban areas as compared to rural areas (74.7 vs 63.6%). Seropositivity rates were related to socioeconomic status only when high status group were compared lower status group (82.5 vs 77%). In addition, we observed a significative trend of increasing seropositivity as level of school education increased. In comparison to the 1974 national survey, this seroepidemiological survey showed a decreased seropositivity for all age groups, even with an increase in the number of susceptible women, particularly in the group less than 20 years old. This study offers seroepidemiologic information about rubella at a national and regional level.

摘要

为了更好地了解墨西哥这种传染病的流行病学情况,在农村人口中开展了一项风疹血清流行病学调查。1987年至1988年期间,从32个联邦州收集了24331份10至44岁女性的血清样本。通过血凝抑制试验检测样本中的风疹抗体,滴度1:8及以上被视为阳性;79.96%(95%置信区间,7.5 - 80.5%)的女性血清呈阳性,血清阳性率随年龄增长而升高,从10至14岁年龄组的69.26%升至40至44岁年龄组的87.84%。南部各州的血清阳性率低于北部各州,城市地区高于农村地区(82.4%对76.6%);城市地区14岁以下女孩与农村地区相比,血清阳性率存在统计学显著差异(74.7%对63.6%)。仅在将高社会经济地位组与低社会经济地位组进行比较时,血清阳性率才与社会经济地位相关(82.5%对77%)。此外,我们观察到随着学校教育水平的提高,血清阳性率有显著上升趋势。与1974年的全国调查相比,此次血清流行病学调查显示所有年龄组的血清阳性率均有所下降,即使易感女性数量有所增加,尤其是20岁以下的群体。这项研究提供了国家和地区层面有关风疹的血清流行病学信息。

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