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[先天性弓形虫病]

[Congenital toxoplasmosis].

作者信息

Conyn-van Spaendonck M A, van Knapen F, de Jong P T

机构信息

Laboratorium voor Parasitologie en Mycologie, RIVM, Bilthoven.

出版信息

Tijdschr Kindergeneeskd. 1990 Dec;58(6):227-33.

PMID:2089735
Abstract

Congenital toxoplasmosis is characterized by the classical triads: hydrocephaly, chorioretinitis and intracerebral calcifications. In fact it is an uncommon manifestation of congenital infection with the parasite Toxoplasma gondii, that is generally subclinical in the neonatal period. But there is a substantial risk of delayed clinical manifestation due to exacerbation of infection: chorioretinitis with loss of vision. With some case histories the interpretation of serodiagnostic techniques is explained and the necessity of repeated tests up to the age of one year in order to exclude a congenital infection definitely, is emphasized.

摘要

先天性弓形虫病的特征为典型三联征

脑积水、脉络膜视网膜炎和脑内钙化。实际上,它是由刚地弓形虫寄生虫引起的先天性感染的一种罕见表现,在新生儿期通常为亚临床症状。但由于感染加重,存在显著的延迟临床表现风险:脉络膜视网膜炎伴视力丧失。通过一些病例史解释了血清诊断技术的解读,并强调了在一岁前重复检测以明确排除先天性感染的必要性。

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