Conyn-van Spaendonck M A, van Knapen F, de Jong P T
Laboratorium voor Parasitologie en Mycologie, RIVM, Bilthoven.
Tijdschr Kindergeneeskd. 1990 Dec;58(6):227-33.
Congenital toxoplasmosis is characterized by the classical triads: hydrocephaly, chorioretinitis and intracerebral calcifications. In fact it is an uncommon manifestation of congenital infection with the parasite Toxoplasma gondii, that is generally subclinical in the neonatal period. But there is a substantial risk of delayed clinical manifestation due to exacerbation of infection: chorioretinitis with loss of vision. With some case histories the interpretation of serodiagnostic techniques is explained and the necessity of repeated tests up to the age of one year in order to exclude a congenital infection definitely, is emphasized.
脑积水、脉络膜视网膜炎和脑内钙化。实际上,它是由刚地弓形虫寄生虫引起的先天性感染的一种罕见表现,在新生儿期通常为亚临床症状。但由于感染加重,存在显著的延迟临床表现风险:脉络膜视网膜炎伴视力丧失。通过一些病例史解释了血清诊断技术的解读,并强调了在一岁前重复检测以明确排除先天性感染的必要性。