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[生育酚和烟酸对缺血性心脏病患者微循环及血液凝固性的影响]

[The effect of tocopherol and nicotinic acid on the microcirculation and blood coagulability in patients with ischemic heart disease].

作者信息

Chernomorets N N, Kotlubeĭ G V, Vatutin N T, Zhivotovskaia I A, Gnilitskaia V B, Alifanova R E, Lobach E Ia, Mal'tseva N V, Mitrofanov A N

出版信息

Vrach Delo. 1990 Dec(12):6-8.

PMID:2089804
Abstract

Patients with ischemic heart disease were treated by routine techniques (53), using also tocopherol acetate (54) and combination of tocopherol with nicotinic acid (53). Changes of the microcirculatory bed of the bulbar conjunctiva was studied biomicroscopically and in the process of blood coagulation hemoelectrocoagulographically. Complex treatment using tocopherol acetate produced a positive effect on the coagulation properties of the blood and did essentially influence the fibrinolytic activity and microcirculation. Tocopherol plus nicotinic acid resulted in normalization of the blood coagulation process, favoured activation of fibrinolysis and improvement of the microcirculatory bed.

摘要

缺血性心脏病患者采用常规技术进行治疗(53),同时还使用了醋酸生育酚(54)以及生育酚与烟酸的组合(53)。通过生物显微镜检查研究了球结膜微循环床的变化,并在血液凝固过程中通过血液电凝法进行了研究。使用醋酸生育酚的综合治疗对血液的凝固特性产生了积极影响,并对纤维蛋白溶解活性和微循环产生了实质性影响。生育酚加烟酸使血液凝固过程正常化,有利于纤维蛋白溶解的激活和微循环床的改善。

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