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[伴有微循环系统微血栓形成表现的缺血性心脏病中的止血作用]

[Hemostasis in ischemic heart disease with manifestations of microthrombosis in the microcirculatory system].

作者信息

Furkalo N K, Bol'shakova R M, Dukhina M A, Ivashchenko T I

出版信息

Kardiologiia. 1982 Mar;22(3):85-9.

PMID:7077910
Abstract

Blood coagulability was studied in patients with ischaemic heart disease and microthromboses in the microcirculation as seen when examining the vessels of the bulbar conjunctiva. Appearance of single microthrombi in the microcirculatory bed was not accompanied by change of blood coagulability as compared to such patients without microthrombi. With multiple microthrombi increase of haemocoagulation properties and of thrombocyte aggregation was noted, more marked with multiple microthrombi in the venules and capillaries. With further spread of the process to arterioles the hypercoagulation tendencies were retained with signs of utilization of coagulation factors, which can be interpreted as disseminated intravascular coagulation.

摘要

对患有缺血性心脏病且在检查球结膜血管时可见微循环中有微血栓形成的患者进行了血液凝固性研究。与无微血栓形成的此类患者相比,微循环床中单个微血栓的出现并未伴随血液凝固性的改变。当出现多个微血栓时,可观察到血液凝固特性和血小板聚集增加,在小静脉和毛细血管中出现多个微血栓时更为明显。随着病情进一步蔓延至小动脉,高凝倾向持续存在,并伴有凝血因子消耗的迹象,这可解释为弥散性血管内凝血。

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