Godard J, Vedrinne C, Motin J
Service de réanimation, Hôpital Edouard Herriot, Lyon.
Agressologie. 1990;31(8 Spec No):529-31.
During a nine months period, 568 patients entered the Polyvalent Intensive Care Unit and were prospectively studied: 153 became infected and 289 infections were diagnosed. Urinary tract infections (31%) in patients with indwelling catheter, lower respiratory tract infections (22%) in tracheally intubated and ventilated patients and bacteremias (19%) totalized 75% of all I.C.U. acquired infections. Post operative and trauma patients were more frequently infected than medical patients. E. coli (19%), S. aureus (14%), Enterococcus (13%) and P. aeruginosa (12%) were isolated and resistance to antibiotics was not always important. The prescribed treatment was an association of antibiotics in 55% of cases. The group whose patients were infected had a longer stay in I.C.U. and a higher mortality rate than group of uninfected patients.
在九个月的时间里，568名患者进入了综合重症监护病房并接受前瞻性研究：153名患者发生感染，共诊断出289例感染。留置导尿管患者发生尿路感染（31%），气管插管并接受机械通气患者发生下呼吸道感染（22%），菌血症（19%），这三类感染总计占重症监护病房获得性感染的75%。术后患者和创伤患者比内科患者更容易发生感染。分离出大肠杆菌（19%）、金黄色葡萄球菌（14%）、肠球菌（13%）和铜绿假单胞菌（12%），且对抗生素的耐药性并非总是很严重。55%的病例采用联合使用抗生素进行治疗。感染患者组在重症监护病房的住院时间更长，死亡率也高于未感染患者组。
