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[重症监护病房金黄色葡萄球菌感染暴发]

[Outbreak of Staphylococcus aureus infections in an intensive care unit].

作者信息

Legras A, Kerouredan V, Martin C, Catier B, Perrotin D

机构信息

Service de réanimation médicale, de l'hôpital Troussean, Tours.

出版信息

Agressologie. 1990;31(8 Spec No):538-40.

PMID:2089979
Abstract

An outbreak of nosocomial staphylococcal infections occurred over a six months period in an intensive care unit. This outbreak was caused by a single phage type of oxacillin resistant Staphylococcus aureus (SA) which infected ten patients. Six patients had bacteremia with infected catheter, two with urinary tract infection and two patients had a pneumonia. The median SAPS was 13. Four patients died. An epidemiologic study was performed to know SA nasal carriage prevalence of patients and hospital staff. There were seven isolates of SA from 83 hospital staff and three from 20 patients, all with the same phage type 77. Hospital staff and patients colonisation with a same SA strain is a potential reservoir for epidemic nosocomial infections. Prophylactic measures are hygienic measures like handwashing, but perhaps also patients and staff selective decontamination with topical antimicrobial substances.

摘要

在一个重症监护病房,六个月内发生了一起医院内葡萄球菌感染暴发事件。此次暴发是由单一噬菌体类型的耐苯唑西林金黄色葡萄球菌(SA)引起的,该菌感染了10名患者。6名患者发生了伴有感染导管的菌血症,2名患者发生了尿路感染,2名患者发生了肺炎。简化急性生理学评分(SAPS)中位数为13。4名患者死亡。进行了一项流行病学研究,以了解患者和医院工作人员鼻腔携带SA的患病率。83名医院工作人员中有7株SA分离株,20名患者中有3株,所有分离株噬菌体类型均为77。医院工作人员和患者被同一株SA定植是医院感染流行的一个潜在传染源。预防措施是洗手等卫生措施,但也许还包括对患者和工作人员使用局部抗菌物质进行选择性去污。

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