Bittencourt A L, Roters F A, da Silva H C
Faculdade de Medicina da Universidade Federal da Bahia, Salvador, BA.
Arq Bras Cardiol. 1990 Nov;55(5):301-3.
A comparison between pathological features of chronic chagasic cardiomyopathy (CCC) in adolescents and adults.
Adolescents under the age of 15, with amastigote trypanosomal forms in the myocardium, a positive xenodiagnosis and/or serology for trypanosoma cruzi infection, were selected from 4.583 necropsies performed between 1958-86 at the Professor Edgard Santos Hospital in Bahia, Brazil.
Nine CCC cases between the ages of 12 and 15 years were identified. Mean heart weight was under twice normal. Intracardiac thrombi were present in five (55.6%), apical left ventricle aneurysm in four (44.4%) and parasites in the myocardium in three (33.3%) cases. Systemic or pulmonary thromboembolism was found in six (66.7%) patients. Mitral regurgitation was present in six (66.7%) cases, two with valvar anatomic alterations.
Pathological features of CCC in adolescents did not differ from those found in adult patients.
比较青少年和成人慢性恰加斯病性心肌病(CCC)的病理特征。
从1958年至1986年在巴西巴伊亚州埃德加德·桑托斯教授医院进行的4583例尸检中,选取15岁以下、心肌中有无鞭毛体锥虫形态、克氏锥虫感染异种诊断和/或血清学呈阳性的青少年。
共识别出9例年龄在12至15岁之间的CCC病例。平均心脏重量低于正常的两倍。5例(55.6%)存在心内血栓,4例(44.4%)有左心室心尖部动脉瘤,3例(33.3%)心肌中有寄生虫。6例(66.7%)患者出现系统性或肺血栓栓塞。6例(66.7%)存在二尖瓣反流,其中2例有瓣膜解剖改变。
青少年CCC的病理特征与成年患者无异。