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[眼眶顶点罕见部位的颅骨结节病]

[Cranial sarcoidosis with an unusual location in the orbital vertex].

作者信息

Queimadelos V, Ortiz Arduan A, Castrillo J M, Jiménez Casado M

机构信息

Servicio de Neurorradiología, Fundación Jiménez Díaz, Madrid.

出版信息

Rev Clin Esp. 1990 Nov;187(8):399-403.

PMID:2091133
Abstract

Bone sarcoidosis preferentially localizes in skull bones with long lasting skin lesions, (its manifestation in skull are rare and there are only 12 or 13 published cases) and the bone involvement of the cranial basis has been referred, until now, as extensive lesions of granulomas localized in neighbouring structures. We present a case of cranial basis granulomatosis, in a patient diagnosed of multiple sarcoidosis by repetitive biopsies of lymph nodes, liver, and skin with chronic skin lesions, the rare localization of which in the orbital vertex with an original bone procedence, is discussed in the neuroradiologic findings. Such rareness has been found in a carrier of a form of common variable immunodeficiency, a disease which is also rare.

摘要

骨结节病好发于伴有长期皮肤病变的颅骨(其在颅骨的表现罕见,仅有12或13例已发表病例),迄今为止,颅底的骨受累一直被认为是局限于相邻结构的广泛肉芽肿病变。我们报告1例颅底肉芽肿病患者,该患者通过对淋巴结、肝脏和有慢性皮肤病变的皮肤进行重复活检诊断为多发性结节病,其在眶尖的罕见定位且起源于骨,在神经放射学检查结果中进行了讨论。这种罕见情况见于一种常见可变免疫缺陷形式的携带者,而这种疾病本身也很罕见。

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