Kershenobich D, Hurtado R, Collawn C, Bobadilla J, Cabrera G, Borovoy J, Borbolla R, Sixtos S, Guevara L, Reynoso E
Departamento de Gastroenterología, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
Rev Invest Clin. 1990 Oct-Dec;42(4):251-6.
To determine the prevalence of serological markers for hepatitis B infection among health care workers (HCW) in Mexico we surveyed 1072 volunteers from 26 hospitals in 12 states, from which only 1017 fulfilled the inclusion criteria: 82 patients (8.1%) were excluded because of lipemic and/or hemolyzed serum, leaving 935 persons in the study. The study population consisted of physicians, nurses, laboratory chemists, health laboratory technicians and odontologists. All of them had been working in their respective fields and in contact with biological materials for at least 12 months. None of them had been vaccinated for hepatitis B. We determined the presence of HBsAg and anti-HBs by the ELISA method. The participants' mean age was 31.4 years (range: 18-72) and their mean working time was 7.8 years. 615 were female and 320 male. The HBsAg was positive in 11 (1.2%) and the anti-HBs in 91 cases (9.7%). These results suggest that HCW in Mexico have a greater relative risk of becoming infected with the HB virus than the general population. Relative risks were particularly higher for the health laboratory technicians and the physicians. These results confirm that biohazard measures must be reinforced and that the application of HB virus vaccine could be recommended for health care workers.
为确定墨西哥医护人员中乙肝感染血清学标志物的流行情况,我们对来自12个州26家医院的1072名志愿者进行了调查,其中只有1017人符合纳入标准:82名患者(8.1%)因血清脂血和/或溶血被排除,最终935人纳入研究。研究人群包括医生、护士、化验员、卫生检验技术员和牙医。他们均在各自领域工作且接触生物材料至少12个月。他们均未接种过乙肝疫苗。我们采用ELISA法检测HBsAg和抗-HBs的存在情况。参与者的平均年龄为31.4岁(范围:18 - 72岁),平均工作时间为7.8年。女性615人,男性320人。HBsAg阳性11人(1.2%),抗-HBs阳性91例(9.7%)。这些结果表明,墨西哥的医护人员感染乙肝病毒的相对风险高于普通人群。卫生检验技术员和医生的相对风险尤其更高。这些结果证实必须加强生物危害防护措施,并建议医护人员接种乙肝病毒疫苗。