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[胃黏膜中幽门螺杆菌的检测——与胃镜检查结果及胃炎程度的关系]

[Detection of Campylobacter pylori in gastric mucosa--relation to gastroscopy findings and degree of gastritis].

作者信息

Häntzschel U, Mehlhorn J, Schreckenbach U, Voigt H U

机构信息

Abt. Gastroenterologie der Klinik für Innere Medizin, Bezirkskrankenhaus, Neubrandenburg, Bundesrepublik Deutschland.

出版信息

Gastroenterol J. 1990;50(4):163-8.

PMID:2091669
Abstract

In 862 unselected gastroscopies we could confirm the high percentage of campylobacter pylori infection in the antral gastric mucosa strongly associated with chronic superficial gastritis and active inflammatory signs. Significant correlation with age concerned the normal findings only. In patients with duodenal ulcers we found in 91% gastritis and in 88% campylobacter pylori in antral mucosa. A small group with duodenal ulcers was campylobacter pylori-negative as well as without gastritis signs. Comparing the antrum and corpus gastric mucosa (250 pat.) the antral mucosa was representative for the whole stomach in view of gastritis and campylobacter pylori test, sufficiently for practical use. Between the test methods (culture, urease, microscopy) we favoured the microscopic test.

摘要

在862例未经挑选的胃镜检查中,我们证实胃窦部胃黏膜中幽门弯曲菌感染率很高,且与慢性浅表性胃炎及活动性炎症体征密切相关。仅正常检查结果与年龄有显著相关性。在十二指肠溃疡患者中,我们发现91%有胃炎,88%胃窦黏膜中有幽门弯曲菌。一小部分十二指肠溃疡患者幽门弯曲菌呈阴性,且无胃炎体征。比较胃窦和胃体黏膜(250例患者),就胃炎和幽门弯曲菌检测而言,胃窦黏膜可代表整个胃部情况,足以满足实际应用。在检测方法(培养、尿素酶、显微镜检查)中,我们更倾向于显微镜检查。

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