Delépine N, Delépine G, Desbois J C
Service d'Oncologie, Hôpital Robert Debré, Paris, France.
Biomed Pharmacother. 1990;44(5):249-56. doi: 10.1016/0753-3322(90)90149-4.
The prognosis of Ewing's sarcoma, the first malignant tumor in children under 10, has improved dramatically in the last 10 yrs. The authors review the signs and symptoms that permit diagnosis and analyse the improvement in treatment, based on multidrug's combination, neoadjuvant chemotherapy and surgical treatment of the primary. They point out the necessity of closed multidisciplinary co-operation to treat these patients. Under these conditions, disease free survival now reaches more than 90% at 3 years 1/2.
尤因肉瘤是10岁以下儿童的首例恶性肿瘤,在过去10年中其预后有了显著改善。作者回顾了有助于诊断的体征和症状,并基于多药联合、新辅助化疗及原发灶的手术治疗分析了治疗方面的进展。他们指出对于治疗这些患者而言,紧密的多学科合作很有必要。在这些条件下,目前3年半时无病生存率超过90%。