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联合放疗与化疗改善尤因肉瘤的预后(作者译)

[Improved prognosis of Ewing-sarcoma by combined irradiation and chemotherapy (author's transl)].

作者信息

Sauer O

出版信息

Monatsschr Kinderheilkd (1902). 1976 Oct;124(10):679-83.

PMID:979963
Abstract

Until recently Ewing's sarcoma has been considered the most lethal malignant bone tumor with the poorest prognosis. An 8-year-old girl with Ewing's sarcoma is described who survived without recurrent disease for nearly 5 years now. 5-year-survival rates among large groups in the literature are reported, and different kinds of therapy compared. There are indications for a tendency that combined radio- and chemotherapy probably have the best results, since in most cases at the time of diagnosis the tumor already has metastasized or, like Lichtenstein believes, Ewing's sarcoma, primarily is of multicentric origin.

摘要

直到最近,尤因肉瘤一直被认为是最致命的恶性骨肿瘤,预后最差。本文描述了一名患有尤因肉瘤的8岁女孩,她至今已存活近5年且无疾病复发。报告了文献中大型队列的5年生存率,并比较了不同类型的治疗方法。有迹象表明,放化疗联合使用可能效果最佳,因为在大多数情况下,肿瘤在诊断时已经发生转移,或者如利希滕斯坦所认为的,尤因肉瘤主要起源于多中心。

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