含有乙酰基作为酰基部分的半合成GM1神经节苷脂（II3Neu5AcGgOse4Cer）的聚集特性。
Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety.
作者信息
Sonnino S, Cantu L, Corti M, Acquotti D, Kirschner G, Tettamanti G
机构信息
Department of Medical Chemistry and Biochemistry, Medical School, University of Milan, Italy.
出版信息
Chem Phys Lipids. 1990 Nov;56(1):49-57. doi: 10.1016/0009-3084(90)90087-8.
The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodynamic radius and molecular weight of 34 A and 102 kDa, respectively, down to a concentration of 2.0 x 10(-5) M.
通过静态和动态光散射测量以及表面张力实验，研究了含有乙酰基作为酰基部分的GM1神经节苷脂[GM1(乙酰基)]在水溶液中的聚集性质。GM1(乙酰基)自发聚集成小胶束，在浓度低至2.0×10⁻⁵ M时，其流体力学半径和分子量分别为34 Å和102 kDa。
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