Prasad M P, Kalyanasundaram M
Vector Control Research Centre, Pondicherry.
Indian J Med Res. 1990 Nov;91:453-7.
Three controlled release formulations of the insect repellent DEPA (N, N-Diethyl phenylacetamide), Depa-A, Depa-B and Depa-C have been developed and tested on human subjects against Aedes aegypti adult mosquitoes for repellency and the results were compared to those of a solution of DEPA (Depa-0). The increase in the protection time of the formulations, as compared to Depa-0 was compared. Depa-B was found to be effective with a protection time of 7.13 and 6.15 h and percentage increase in protection time of 44.5 and 38.2 at the two application rates of 0.5 and 0.25 mg/cm2 of the repellent. This observation agreed with the studies carried out on the evaporation of the repellent formulations on two models, on adsorbing and nonadsorbing surfaces for the relative adsorption and evaporation by analysing the repellent concentrations, using an infrared spectrophotometer.
已研发出三种驱虫剂DEPA（N，N - 二乙苯基乙酰胺）的控释制剂Depa - A、Depa - B和Depa - C，并在人体受试者上针对埃及伊蚊成虫进行了驱蚊测试，且将结果与DEPA溶液（Depa - 0）的结果进行了比较。比较了这些制剂与Depa - 0相比保护时间的增加情况。发现Depa - B有效，在驱虫剂的两种施用率0.5和0.25 mg/cm²下，保护时间分别为7.13小时和6.15小时，保护时间增加百分比分别为44.5和38.2。该观察结果与在两种模型上对驱虫剂制剂蒸发情况的研究一致，这两种模型分别为吸附表面和非吸附表面，通过使用红外分光光度计分析驱虫剂浓度来研究相对吸附和蒸发情况。
