Department of Psychiatry, University of Texas Medical Branch, Galveston, USA.
J Clin Psychiatry. 2010 Sep;71(9):e23. doi: 10.4088/JCP.9089tx2cc.
Bipolar disorder has been shown to have a chronic course of illness, and children with this disorder are likely to need long-term treatment. Although limited data exist on the efficacy of long-term pharmacotherapy for pediatric bipolar disorder, 5 medications are approved as monotherapy for mixed or manic episodes and 2 are approved as adjunctive treatment. Clinicians should be vigilant in monitoring adverse events in children and adolescents taking psychotropic medications and should consider implementing psychotherapeutic interventions, which can improve youths' symptomatic and functional outcomes.
双相障碍具有慢性病程，此类障碍患儿可能需要长期治疗。虽然关于儿科双相障碍长期药物治疗疗效的数据有限，但有 5 种药物被批准用于混合或躁狂发作的单药治疗，有 2 种药物被批准用于辅助治疗。临床医生应警惕监测接受精神药物治疗的儿童和青少年的不良事件，并考虑实施心理治疗干预，这可以改善青少年的症状和功能结局。
