Department of Biomaterials, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
J Dent Res. 2010 Dec;89(12):1489-93. doi: 10.1177/0022034510384621. Epub 2010 Oct 5.
Microplasma spray equipment to deposit calcium phosphate ceramic (CaP) coatings has been developed. Fifty-six titanium implants were inserted into the mandibles of 7 adult beagle dogs. The implants were either acid-etched (NC), conventionally plasma-sprayed (PS), micro-plasma-sprayed (MPS), or micro-plasma-sprayed (aMPS) only at the apical part. After 6 weeks, implants in one half of the mandible were subjected to load. Fifty-two weeks thereafter, the animals were killed. Regardless of load, bone healing was comparable for all surfaces tested. It was concluded that loading of MPS CaP-coated implants evokes a favorable bone response, and that the bone response does not differ from that of PS CaP-coated implants. However, functional loading of PS as well as MPS CaP-coated implants might be associated with increased crestal bone maintenance as compared with non-coated implants.
已开发出用于沉积钙磷陶瓷（CaP）涂层的微等离子喷涂设备。将 56 个钛植入物植入 7 只成年比格犬的下颌骨中。植入物经过酸蚀（NC）、常规等离子喷涂（PS）、微等离子喷涂（MPS）或仅在根尖部位进行微等离子喷涂（aMPS）处理。6 周后，在下颌骨的一半植入物上施加负荷。此后 52 周，处死动物。无论是否加载，所有测试表面的骨愈合情况都相当。研究结论认为，MPS CaP 涂层植入物的加载会引起有利的骨反应，且该骨反应与 PS CaP 涂层植入物的骨反应无差异。然而，与未涂层植入物相比，PS 以及 MPS CaP 涂层植入物的功能性加载可能与牙槽骨的维持增加相关。
