Department of Periodontology and Biomaterials, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Clin Oral Implants Res. 2010 Feb;21(2):189-200. doi: 10.1111/j.1600-0501.2009.01819.x. Epub 2009 Dec 4.
New microplasma spray (MPS) equipment to deposit calcium phosphate (CaP) ceramic coatings onto titanium substrates has been developed. With this apparatus, it is possible to spray fine particles, as well as to apply textured hydroxylapatite coatings onto titanium surfaces. Moreover, due to the low heat power of the microplasma jet, overheating of the powder particles as well as excessive local overheating of the substrate is reduced. Furthermore, because of the small laminar plasma jet, it is possible to achieve high spray efficiency in the case of spraying of dental implants. Additionally, the low level of noise (25-50 dB) and hardly any dust makes it possible to operate the MSE under normal workroom conditions.
The aim of this study was to examine the biological properties of different MPS - CaP coatings on titanium implants when inserted into the femoral condyle of goats.
For histomorphometrical evaluation as well as mechanical testing, 48 screw-type titanium implants were inserted into the femoral condyles of 12 goats each. The implants were either coated with a conventionally plasma-sprayed CaP ceramic, MPS CaP ceramic, or acid-etched without an additional CaP coating. Six and 12 weeks after implantation, the animals were sacrificed and bone-to-implant contact, amount of bone, as well as mechanical bone fixation were evaluated.
For bone-to-implant contact no statistically significant difference was found between the different CaP coatings. However, statistically significant differences were found between non-coated, acid-etched titanium implants and CaP-coated implants after 6 and 12 weeks of healing. The bone values were not statistically significantly different between the different CaP coatings at 6 and 12 weeks. Furthermore, CaP ceramic-coated implants showed statistically significantly higher torque values compared with the non-coated implants after 6 and at 12 weeks of healing. No significant differences existed between the various types of CaP coatings.
On the basis of our observations, we conclude that conventionally plasma-sprayed CaP ceramic-coated implants, as well as MPS-coated implants have a comparable effect on adjacent bone response.
新的微等离子体喷涂（MPS）设备已被开发出来，用于在钛基体上沉积钙磷（CaP）陶瓷涂层。使用这种设备，可以喷涂细颗粒，也可以在钛表面施加纹理化的羟基磷灰石涂层。此外，由于微等离子体射流的低热功率，减少了粉末颗粒的过热和基体的局部过热。此外，由于小层流等离子体射流，可以在喷涂牙种植体的情况下实现高喷涂效率。此外，低水平的噪音（25-50dB）和几乎没有灰尘，使得 MSE 可以在正常的工作室条件下运行。
本研究旨在研究不同 MPS-CaP 涂层钛种植体植入山羊股骨髁后的生物学性能。
为了进行组织形态计量学评估和力学测试，将 48 个螺钉式钛种植体分别植入 12 只山羊的股骨髁内。种植体分别用传统的等离子喷涂 CaP 陶瓷、MPS CaP 陶瓷或酸蚀处理，不进行额外的 CaP 涂层处理。植入后 6 周和 12 周，处死动物，评估骨与种植体的接触、骨量以及机械骨固定。
对于骨与种植体的接触，不同 CaP 涂层之间没有统计学上的显著差异。然而，在植入后 6 周和 12 周的愈合期，非涂层、酸蚀钛种植体和 CaP 涂层种植体之间存在统计学上的显著差异。在植入后 6 周和 12 周时，不同 CaP 涂层之间的骨值没有统计学上的显著差异。此外，与未涂层种植体相比，CaP 陶瓷涂层种植体在植入后 6 周和 12 周时的扭矩值显著更高。在不同的 CaP 涂层之间没有显著差异。
根据我们的观察，我们得出结论，传统等离子喷涂 CaP 陶瓷涂层种植体和 MPS 涂层种植体对相邻骨反应的影响相当。
