Waisbren S J, Whiting C S, Nadel E R
Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510.
Yale J Biol Med. 1990 Nov-Dec;63(6):549-56.
This study was undertaken to determine if the observed increase in ventilation during passive limb movement was a reflex hyperventilation or a response to an increased metabolic need for oxygen. Experiments on human volunteers were designed to test the hypothesis that the rapid increase of ventilation at the onset of exercise was due to stimulation of the joints. Results of these studies showed significant increases in ventilation, oxygen consumption, carbon dioxide production, ventilation/oxygen consumption ratio, and heart rate compared to rest and recovery values. The data lead to the conclusion that the rapid increase of ventilation at the onset of exercise is a true hyperventilation and that stimulation of the joints can be a significant contributor to increased pulmonary ventilation.
本研究旨在确定被动肢体运动期间观察到的通气增加是反射性过度通气还是对增加的氧代谢需求的反应。针对人类志愿者开展的实验旨在检验运动开始时通气迅速增加是由于关节受到刺激这一假设。这些研究结果表明,与休息和恢复值相比,通气、氧消耗、二氧化碳产生、通气/氧消耗比和心率均显著增加。数据得出的结论是,运动开始时通气的迅速增加是真正的过度通气,关节刺激可能是肺通气增加的一个重要因素。