Department of Psychiatry and Neuroscience, University of North Texas Health Sciences Center, Fort Worth, TX 76107, USA.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2011 Jan;18(1):56-63. doi: 10.1080/13825585.2010.510556. Epub 2010 Sep 30.
Spatial Span subtest of the Wechsler Memory Scale has been viewed as an indicator of working memory and visuospatial processing. The current study examined the impact of cognitive impairment and its severity on Spatial Span performance. A neuropsychological battery including Spatial Span was administered to 538 individuals (65-89) who were grouped by consensus into Alzheimer's disease, Vascular Dementia, Amnestic Mild Cognitive Impairment, Non-Amnestic Mild Cognitive Impairment and cognitively normal. Increase in level of impairment resulted in a decrease in Spatial Span Total Score. A weak relationship between age and Spatial Span Total Score was found. Spatial Span Forward remains relatively stable regardless of level of impairment. Spatial Span Backward was more sensitive to severity. No significant differences were found between individuals diagnosed with Alzheimer's disease and those with Vascular Dementia suggesting similar deficit patterns in the cognitive abilities measured by the Spatial Span. Mild Cognitive Impairment groups and normals did not differ suggesting visuospatial processes are not affected early in the dementing process.
韦氏记忆量表的空间广度分测验被视为工作记忆和视空间处理的指标。本研究探讨了认知障碍及其严重程度对空间广度表现的影响。一组神经心理学测试，包括空间广度，被用于 538 名（65-89 岁）被分为阿尔茨海默病、血管性痴呆、遗忘型轻度认知障碍、非遗忘型轻度认知障碍和认知正常的个体。认知障碍程度的增加导致空间广度总得分的下降。发现年龄和空间广度总得分之间存在弱相关。空间广度前向测试结果相对稳定，与认知障碍程度无关。空间广度后向测试结果对严重程度更敏感。在诊断为阿尔茨海默病和血管性痴呆的个体之间未发现显著差异，这表明在空间广度测量的认知能力方面存在相似的缺陷模式。轻度认知障碍组和正常组之间没有差异，这表明在痴呆过程的早期，视空间过程不受影响。
