Economou Alexandra, Papageorgiou Sokratis, Karageorgiou Clementine
The University of Athens, Greece.
J Clin Exp Neuropsychol. 2006 May;28(4):528-35. doi: 10.1080/13803390590949340.
Performance on neuropsychological tests is affected by age and education, which makes the early detection of cognitive impairment difficult when assessing individuals of varying levels of education. We examined the effects of age, education, and gender on three memory indexes of the Wechsler Memory Scale-III, Delayed Memory, Working Memory and the difference between Working-Delayed Memory in a sample of patients with amnestic Mild Cognitive Impairment, patients with mild probable Alzheimer's disease, and a nondemented elderly comparison group. Whereas Delayed and Working Memory scores were affected by participant type, age, and education, the Working-Delayed Memory difference score was affected by participant type, only. Our preliminary conclusions, pending replication of the findings with a larger sample, are that working-delayed memory difference was sensitive to early memory decline without being affected by age and education.
神经心理学测试的表现会受到年龄和教育程度的影响，这使得在评估不同教育水平的个体时，早期发现认知障碍变得困难。我们在遗忘型轻度认知障碍患者、轻度可能的阿尔茨海默病患者以及非痴呆老年对照组样本中，研究了年龄、教育程度和性别对韦氏记忆量表第三版的三个记忆指标（延迟记忆、工作记忆以及工作记忆与延迟记忆之差）的影响。虽然延迟记忆和工作记忆得分受参与者类型、年龄和教育程度的影响，但工作记忆与延迟记忆的差异得分仅受参与者类型的影响。在通过更大样本对研究结果进行重复验证之前，我们的初步结论是，工作记忆与延迟记忆的差异对早期记忆衰退敏感，且不受年龄和教育程度的影响。
