Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY 10467, USA.
J Addict Dis. 2010 Oct;29(4):461-5. doi: 10.1080/10550887.2010.509281.
Patients with chronic hepatitis C virus (HCV) are at increased risk for complications of liver disease if they become infected with the hepatitis A (HAV) or hepatitis B (HBV) viruses. The authors examined the rates of testing for HAV, HBV, and HCV, as well as rates of vaccination against HAV and HBV in patients with chronic HCV in a random sample (N = 207) of medical records of patients enrolled in a methadone maintenance program. Almost all patients reviewed were tested for HAV, HBV, and HCV. Of the 111 patients with chronic HCV, 53 (48.6%) and 68 (63%) lacked immunity to HAV and HBV, respectively. Of those lacking immunity, 29 (54.7%) and 2 (2.9%) were vaccinated for HAV and HBV, respectively. Despite high rates of testing for HAV, HBV, and HCV at a methadone maintenance program, approximately half of those with chronic HCV eligible for the HAV vaccine received it, and few of those eligible for HBV vaccine received it.
患有慢性丙型肝炎病毒（HCV）的患者，如果感染了甲型肝炎（HAV）或乙型肝炎（HBV）病毒，患肝病并发症的风险会增加。作者检查了在美沙酮维持治疗计划中招募的患者的病历随机样本（N=207）中，慢性 HCV 患者中 HAV、HBV 和 HCV 的检测率，以及 HAV 和 HBV 疫苗的接种率。几乎所有接受检查的患者都接受了 HAV、HBV 和 HCV 的检测。在 111 名慢性 HCV 患者中，分别有 53 名（48.6%）和 68 名（63%）对 HAV 和 HBV 缺乏免疫力。在那些缺乏免疫力的患者中，分别有 29 名（54.7%）和 2 名（2.9%）接种了 HAV 和 HBV 疫苗。尽管在美沙酮维持治疗计划中对 HAV、HBV 和 HCV 进行了高频率的检测，但大约一半有资格接种 HAV 疫苗的慢性 HCV 患者接受了接种，而有资格接种 HBV 疫苗的患者中很少有人接受了接种。
