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17-year-old girl with headache and complex partial seizure.17 岁女孩,头痛,复杂部分性发作。
Brain Pathol. 2010 Nov;20(6):1111-4. doi: 10.1111/j.1750-3639.2010.00435.x.
2
Supratentorial Pure Cortical Ependymoma: An Unusual Lesion Causing Focal Motor Aware Seizure.幕上纯皮质室管膜瘤:一种导致局灶性运动性觉知癫痫发作的罕见病变。
J Neurosci Rural Pract. 2018 Apr-Jun;9(2):264-267. doi: 10.4103/jnrp.jnrp_31_18.
3
Parenchymal anaplastic ependymoma with intratumoral hemorrhage: a case report.伴有瘤内出血的实质间变性室管膜瘤:一例报告
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Giant cell ependymoma of the thoracic spinal cord.胸髓巨细胞室管膜瘤。
Acta Neurol Belg. 2012 Mar;112(1):71-5. doi: 10.1007/s13760-012-0038-9. Epub 2012 Feb 7.
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Supratentorial pure cortical ependymoma.幕上纯皮质室管膜瘤。
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Papillary ependymoma with unique superficial cortical location: immunohistochemical and ultrastructural studies. A case report.具有独特表浅皮质位置的乳头状室管膜瘤:免疫组织化学和超微结构研究。病例报告。
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Intracranial peripheral-type primitive neuroectodermal tumor.颅内外周型原始神经外胚层肿瘤。
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Long-term survival following gross total resection of pediatric supratentorial ependymomas without adjuvant therapy.小儿幕上室管膜瘤全切术后无辅助治疗的长期生存情况。
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Cytologic findings in malignant ependymoma: a case report.恶性室管膜瘤的细胞学表现:一例报告
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Supratentorial Cortical Ependymomas: A Retrospective Series of 13 Cases at a Single Center.幕上皮质室管膜瘤:单中心13例回顾性研究系列
World Neurosurg. 2018 Apr;112:e772-e777. doi: 10.1016/j.wneu.2018.01.153. Epub 2018 Jan 31.

引用本文的文献

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Supratentorial extra-axial anaplastic ependymoma: a rare case report.幕上脑外间变性室管膜瘤:一例罕见病例报告
Ann Med Surg (Lond). 2023 Sep 5;85(11):5634-5640. doi: 10.1097/MS9.0000000000000536. eCollection 2023 Nov.
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Extra-axial giant falcine ependymoma with ultra-rapid growth in child: Uncommon entity with literature review.儿童超快速生长的轴外巨大镰旁室管膜瘤:罕见病例并文献复习
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Cortical anaplastic ependymoma with significant desmoplasia: a case report and literature review.伴有显著促纤维增生的皮质间变性室管膜瘤:一例报告及文献复习
Case Rep Oncol Med. 2013;2013:354873. doi: 10.1155/2013/354873. Epub 2013 Dec 16.

本文引用的文献

1
The history of ependymoma management.室管膜瘤治疗的历史。
Childs Nerv Syst. 2009 Oct;25(10):1167-83. doi: 10.1007/s00381-009-0900-0. Epub 2009 May 21.
2
Intracranial ependymomas in children: society of pediatric oncology experience with postoperative hyperfractionated local radiotherapy.儿童颅内室管膜瘤:儿科肿瘤学会术后超分割局部放疗经验
Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1536-42. doi: 10.1016/j.ijrobp.2008.09.051. Epub 2009 Apr 11.
3
Incidence patterns for ependymoma: a surveillance, epidemiology, and end results study.室管膜瘤的发病模式:一项监测、流行病学及最终结果研究。
J Neurosurg. 2009 Apr;110(4):725-9. doi: 10.3171/2008.9.JNS08117.
4
Supratentorial ectopic cortical ependymoma occurring with intratumoral hemorrhage.幕上异位皮质型室管膜瘤伴瘤内出血。
Brain Tumor Pathol. 2007;24(1):35-40. doi: 10.1007/s10014-007-0215-3. Epub 2007 May 25.
5
Radial glia cells are candidate stem cells of ependymoma.放射状胶质细胞是室管膜瘤的候选干细胞。
Cancer Cell. 2005 Oct;8(4):323-35. doi: 10.1016/j.ccr.2005.09.001.
6
Supratentorial cortical ependymoma: report of three cases.幕上皮质室管膜瘤:三例报告。
Neurosurgery. 2005 Jul;57(1):E192; discussion E192. doi: 10.1227/01.neu.0000164171.29292.d6.
7
Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma.局部室管膜瘤儿科患者适形放射治疗II期试验的初步结果及放射相关中枢神经系统效应评估。
J Clin Oncol. 2004 Aug 1;22(15):3156-62. doi: 10.1200/JCO.2004.11.142.
8
Supratentorial ependymomas in adult patients.成年患者的幕上室管膜瘤
Neurosurgery. 1999 Apr;44(4):721-31. doi: 10.1097/00006123-199904000-00018.
9
Survival and prognostic factors following radiation therapy and chemotherapy for ependymomas in children: a report of the Children's Cancer Group.儿童室管膜瘤放疗和化疗后的生存及预后因素:儿童癌症研究组报告
J Neurosurg. 1998 Apr;88(4):695-703. doi: 10.3171/jns.1998.88.4.0695.
10
Supratentorial ectopic ependymoma.幕上异位室管膜瘤
Can J Neurol Sci. 1995 Nov;22(4):316-9. doi: 10.1017/s0317167100039561.

17 岁女孩,头痛,复杂部分性发作。

17-year-old girl with headache and complex partial seizure.

机构信息

Department of Neurosurgery, Severance Hospital, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Brain Pathol. 2010 Nov;20(6):1111-4. doi: 10.1111/j.1750-3639.2010.00435.x.

DOI:10.1111/j.1750-3639.2010.00435.x
PMID:20925697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8094711/
Abstract

Supratentorial cortical ependymoma is a rare clinical entity where ependymoma occurring in the cortex without any connection to the ventricular system since ependymoma usually arises from the lining of the ventricular system or central canal of spinal cord. There have been 14 such cases reported in the literature.We report the first case of a supratentorial extraaxial cortical anaplastic ependymoma with minimal cortical attachment in a 17-years-old girl, presented with headache and complex partial seizure. Histological features of anaplasia including numerous mitoses, necrosis and high Ki-67 lead to postoperative adjuvant radiation therapy although gross total resection was achieved.

摘要

幕上皮质室管膜瘤是一种罕见的临床实体,其中发生在皮质而与脑室系统没有任何联系的室管膜瘤,因为室管膜瘤通常起源于脑室系统或脊髓中央管的衬里。文献中已经报道了 14 例此类病例。我们报告了首例 17 岁女孩幕上额外轴皮质间变性室管膜瘤的病例,该患者表现为头痛和复杂部分性癫痫发作。组织学特征包括大量有丝分裂、坏死和高 Ki-67,尽管实现了大体全切除,但术后仍需要辅助放疗。