Department of Neurosurgery, Severance Hospital, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Brain Pathol. 2010 Nov;20(6):1111-4. doi: 10.1111/j.1750-3639.2010.00435.x.
Supratentorial cortical ependymoma is a rare clinical entity where ependymoma occurring in the cortex without any connection to the ventricular system since ependymoma usually arises from the lining of the ventricular system or central canal of spinal cord. There have been 14 such cases reported in the literature.We report the first case of a supratentorial extraaxial cortical anaplastic ependymoma with minimal cortical attachment in a 17-years-old girl, presented with headache and complex partial seizure. Histological features of anaplasia including numerous mitoses, necrosis and high Ki-67 lead to postoperative adjuvant radiation therapy although gross total resection was achieved.
幕上皮质室管膜瘤是一种罕见的临床实体,其中发生在皮质而与脑室系统没有任何联系的室管膜瘤,因为室管膜瘤通常起源于脑室系统或脊髓中央管的衬里。文献中已经报道了 14 例此类病例。我们报告了首例 17 岁女孩幕上额外轴皮质间变性室管膜瘤的病例,该患者表现为头痛和复杂部分性癫痫发作。组织学特征包括大量有丝分裂、坏死和高 Ki-67,尽管实现了大体全切除,但术后仍需要辅助放疗。