以色列儿童中与年龄相关的人细小病毒B19免疫球蛋白G血清阳性率
Age-related immunoglobulin G seroprevalence of human parvovirus B-19 in Israeli children.
作者信息
Miron Dan, Horovitz Yoseph, Luder Anthony, Ohnona Frederic S, Schlesinger Yechiel
机构信息
Department of Pediatrics A, HaEmek Medical Center, Afula, Israel.
出版信息
Isr Med Assoc J. 2010 May;12(5):277-9.
BACKGROUND
Human parvovirus B19 is a global and common infectious pathogen in humans, particularly in children.
OBJECTIVES
To assess the immunoglobulin G3 seroprevalence of B19 in children in Israel.
METHODS
Overall, 128 previously healthy children (1.5-17 years old) hospitalized for various diseases other than acute human parvovirus B19 infection were assessed for IgG to the virus by enzyme-linked immunosorbent assay.
RESULTS
The IgG seroprevalence increased from 22% in children aged 1.5-9 years to 52% in older children (P = 0.001).
CONCLUSIONS
Our data suggest that most acute parvovirus B19 infections in Israel occur in the early school years, and that by 18 years of age 50% of Israeli children have been infected by the virus.
背景
人细小病毒B19是一种在全球范围内常见的人类感染性病原体，尤其在儿童中多见。
目的
评估以色列儿童中B19的免疫球蛋白G3血清阳性率。
方法
总共128名先前健康的儿童（1.5 - 17岁）因除急性人细小病毒B19感染以外的各种疾病住院，通过酶联免疫吸附测定法评估其针对该病毒的IgG。
结果
IgG血清阳性率从1.5 - 9岁儿童中的22%上升至大龄儿童中的52%（P = 0.001）。
结论
我们的数据表明，以色列大多数急性细小病毒B19感染发生在学龄早期，到18岁时，50%的以色列儿童已感染该病毒。
Zotero 插件