Ooi S L, Hooi P S, Chua B H, Lam S K, Chua K B
Department of Allied Health Sciences, University of Malaya Medical Centre, 50603, Kuala Lumpur.
Med J Malaysia. 2002 Mar;57(1):97-103.
A seroepidemiological study carried out on 800 stored serum samples collected between January 1999 to December 2000 derived from an urban population in Malaysia showed that the overall seropositive rate of human paravovirus B19 infection was 37.6%, with an overall geometric mean titre (GMT) of 18.3 IU. The seropositive rates of B19 among the male and female populations were 39.0% and 36.3% respectively. The seropositive rates among the racial groups were 37.2%, 38.2%, 38.1% and 29.4% respectively for the Malays, Chinese, Indians and other races. There was no statistical significant gender and racial differences in the B19 seropositive rates. When compared with the seroprevalence of B19 infection in other Asian countries, the seropositive rate of B19 in Malaysia was low in the younger age group and increased steadily with age. The unusual finding in this study was the presence of a high seropositive rate in those between six months to five years of age, especially in children in the one year old age group.
一项针对1999年1月至2000年12月间从马来西亚城市人口中收集的800份储存血清样本进行的血清流行病学研究表明，人类细小病毒B19感染的总体血清阳性率为37.6%，总体几何平均滴度（GMT）为18.3 IU。男性和女性人群中B19的血清阳性率分别为39.0%和36.3%。马来人、华人、印度人和其他种族的血清阳性率分别为37.2%、38.2%、38.1%和29.4%。B19血清阳性率在性别和种族上没有统计学显著差异。与其他亚洲国家B19感染的血清流行率相比，马来西亚B19的血清阳性率在较年轻年龄组中较低，并随年龄稳步上升。本研究中不寻常的发现是6个月至5岁人群，尤其是1岁年龄组儿童中存在较高的血清阳性率。
