俄罗斯圣彼得堡艾滋病患者中的微孢子虫病和隐孢子虫病：艾滋病患者血清样本中微孢子虫和微小隐孢子虫的血清学鉴定
Microsporidiosis and Cryptosporidiosis in HIV/AIDS Patients in St. Petersburg, Russia: Serological identification of microsporidia and Cryptosporidium parvum in sera samples from HIV/AIDS patients.
作者信息
Kucerova Z, Sokolova O I, Demyanov A V, Kvac M, Sak B, Kvetonova D, Secor W E
机构信息
Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
出版信息
AIDS Res Hum Retroviruses. 2011 Jan;27(1):13-5. doi: 10.1089/aid.2010.0132. Epub 2010 Oct 7.
To determine seroprevalence of the opportunistic organisms Cryptosporidium parvum and microsporidia (Encephalitozoon cuniculi, E. intestinalis, E. hellem, and Enterocytozoon bieneusi) in Russian HIV/AIDS patients, we evaluated 46 sera from HIV/AIDS patients from the S.P. Botkin Clinical Infectious Diseases Hospital, St. Petersburg, Russia. Five (10.9%) sera were seropositive for E. cuniculi and 19 (41.3%) were positive for C. parvum by ELISA. By IFAT, 6 (13.0%) sera were seropositive for E. bieneusi, 4 (8.7%) for E. intestinalis, and 9 (19.6%) for E. hellem. This study is the first report to estimate the prevalence of infection with Cryptosporidium and microsporidia among Russian HIV/AIDS patients.
为确定俄罗斯艾滋病毒/艾滋病患者中机会性致病生物微小隐孢子虫和微孢子虫（兔脑炎微孢子虫、肠脑炎微孢子虫、海伦脑炎微孢子虫和比氏肠细胞微孢子虫）的血清阳性率，我们评估了来自俄罗斯圣彼得堡S.P. 博特金临床传染病医院的46例艾滋病毒/艾滋病患者的血清。通过酶联免疫吸附测定法（ELISA），5份（10.9%）血清兔脑炎微孢子虫呈血清阳性，19份（41.3%）微小隐孢子虫呈阳性。通过间接荧光抗体试验（IFAT），6份（13.0%）血清比氏肠细胞微孢子虫呈血清阳性，4份（8.7%）肠脑炎微孢子虫呈阳性，9份（19.6%）海伦脑炎微孢子虫呈阳性。本研究是首份评估俄罗斯艾滋病毒/艾滋病患者中隐孢子虫和微孢子虫感染率的报告。
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