Bańkowski E, Rzeczycki W, Nowak H K, Jodczyk K J
Mol Cell Biochem. 1978 Jun 28;20(2):77-83. doi: 10.1007/BF00241385.
Rat kidney fibroblasts transformed with SV-40 produce "in vitro" a significantly lower amount of hydroxyproline-containing material which is collagenase sensitive as compared to normal cells. In contrast to normal fibroblast cultures, no collagenous material was found by histochemical methods in intercellular spaces of transformed cultures.
用SV - 40转化的大鼠肾成纤维细胞在“体外”产生的含羟脯氨酸物质的量明显低于正常细胞，且该物质对胶原酶敏感。与正常成纤维细胞培养物不同，通过组织化学方法在转化培养物的细胞间隙中未发现胶原物质。
