Björnsdóttir Ingunn, Kristinsson Karl G, Hansen Ebba Holme
Department of Pharmacology and Pharmacotherapy, Section for Social Pharmacy, University of Copenhagen, Copenhagen, Denmark.
Pharm World Sci. 2010 Dec;32(6):805-14. doi: 10.1007/s11096-010-9441-6. Epub 2010 Oct 8.
Antibiotics may frequently be prescribed on the basis of vague diagnoses, possibly resulting in unnecessary antimicrobial resistance. Our aim is to map general practitioners' (GPs') decision-making for common infections, exploring their diagnostic basis for antibiotic prescriptions.
General practice in Iceland.
Ten in-depth qualitative interviews with, and three observations of, GPs in 1995. Diagnostic issues extracted and analysed. In 2006, eight GPs commented on analysis and updated (email/telephone).
Diagnostic variability and reasons for prescribing antibiotics, consistency or changes over time.
Wide variations were uncovered in diagnostic procedures, although each GP remained consistent through time. Some GPs had developed "rules-of-thumb". They often balanced risks against issues like money, time, need for the workforce (perceived importance of the patient's job), client's need for job/earnings (perceived ability to afford a sick day) and doctor-patient relationship (risk of refusal adversely affecting the relationship). Perceptions of risk varied from focusing on resistance development to focusing on possible harm from untreated infections, also ranging between considering both to worrying about neither. Changes over time were not prominent but included increased point-of-care testing and the perception by GPs that patients were increasingly willing to "wait and see".
Large variability and individuality characterized the GPs' diagnostic procedures, contrasted by consistency through time. If modification of diagnostic routines is needed, provision of "scientific facts" and technological aids is insufficient. A prerequisite for changing practice is GPs' acceptance of accuracy of information and of reliability, applicability, and relevance of technology, for physician and/or patient.
抗生素的处方往往基于模糊的诊断,这可能导致不必要的抗菌药物耐药性。我们的目的是梳理全科医生(GP)对常见感染的决策过程,探究他们开具抗生素处方的诊断依据。
冰岛的全科医疗。
1995年对全科医生进行了10次深入的定性访谈,并进行了3次观察。提取并分析诊断问题。2006年,8名全科医生对分析结果进行了评论并更新(通过电子邮件/电话)。
诊断的变异性、开具抗生素的原因、随时间的一致性或变化情况。
尽管每位全科医生在不同时间保持一致,但诊断程序存在很大差异。一些全科医生制定了“经验法则”。他们经常在风险与金钱、时间、劳动力需求(患者工作的感知重要性)、患者对工作/收入的需求(感知的请病假能力)以及医患关系(拒绝治疗可能对关系产生不利影响的风险)等因素之间进行权衡。对风险的认知各不相同,从关注耐药性的产生到关注未治疗感染可能带来的危害,也包括同时考虑两者或两者都不担心。随时间的变化并不显著,但包括即时检验的增加以及全科医生认为患者越来越愿意“观望”。
全科医生的诊断程序具有很大的变异性和个体性,与之形成对比的是随时间的一致性。如果需要修改诊断常规,仅提供“科学事实”和技术辅助是不够的。改变医疗行为的一个先决条件是全科医生接受信息的准确性以及技术对医生和/或患者的可靠性、适用性和相关性。