Stier B, Schröder T, Matschke H J, Haas W
Neurologische Klinik, Zentralklinik für Psychiatrie und Neurologie Wilhelm Griesinger Berlin.
Psychiatr Neurol Med Psychol (Leipz). 1990 Nov;42(11):693-8.
Localised hyperhidrosis is comparatively rare among the vegetative disorders. A case of pathological gustatory and olfactory sudation is reported, with the sequence of symptoms corresponding to that of the Frey syndrome. Working from the reflex nature of the phenomen, the paper puts forward a model to account for the delayed onset of the manifestation following a peripheral lesion. It is assumed that readjustment of the reflex excitation level takes place according to a modification in peripheral afference, and that a decompensation of the central control mechanisms results in a pathological enhancement of the reflex. The hypothesis of peripheral efferentisl denervation hypersensitivity appears insufficient to account for the delay in manifestation, or even to account for the classic Frey syndrome following an affection of the parotid gland.
局限性多汗症在植物神经功能紊乱中相对少见。本文报告一例病理性味觉性和嗅觉性出汗病例，其症状顺序与弗雷综合征相符。基于该现象的反射本质，本文提出一个模型来解释周围神经损伤后症状延迟出现的原因。假定反射兴奋水平根据外周传入的改变进行调整，并且中枢控制机制失代偿导致反射病理性增强。外周传出神经去神经超敏反应假说似乎不足以解释症状出现的延迟，甚至无法解释腮腺病变后典型的弗雷综合征。
