Department of Information Management, Ching Yun University, Taiwan.
Comput Methods Programs Biomed. 2012 Jun;106(3):234-48. doi: 10.1016/j.cmpb.2010.09.002. Epub 2010 Oct 8.
Enormous numbers of digital mammograms have been produced in hospitals and breast screening centers. To exploit those valuable resources in aiding diagnoses and research, content-based mammogram retrieval systems are required to effectively access the mammogram databases. This paper presents a content-based mammogram retrieval system, which allows medical professionals to seek mass lesions that are pathologically similar to a given example. In this retrieval system, shape and margin features of mass lesions are extracted to represent the characteristics of mammographic lesions. To compare the similarity between the query example and any lesion within the databases, this study proposes a similarity measure scheme which involves the hierarchical arrangement of mammographic features and a weighting distance measure. This makes similarity measure of the retrieval system consistent with the way radiologists observe mass lesions. This study used the DDSM dataset to evaluate the effectiveness of the extracted shape feature and margin feature, respectively. Experimental results demonstrate that, when Zernike moments are used, round-shape masses are the most discriminative among four types of shape; the circumscribed-margin masses can be effectively discriminated among the four types of margins. Moreover, the result also shows that, when retrieving round-shape and circumscribed margin masses, this retrieval system can achieve the highest precision among all mass lesion types.
大量的数字乳腺 X 线照片已经在医院和乳腺筛查中心产生。为了利用这些有价值的资源来辅助诊断和研究,需要基于内容的乳腺 X 线照片检索系统来有效地访问乳腺 X 线照片数据库。本文提出了一种基于内容的乳腺 X 线照片检索系统,允许医疗专业人员寻找与给定示例在病理上相似的大量病变。在这个检索系统中,提取肿块病变的形状和边缘特征来表示乳腺病变的特征。为了比较查询示例与数据库中任何病变之间的相似性,本研究提出了一种相似性度量方案,涉及乳腺特征的分层排列和加权距离度量。这使得检索系统的相似性度量与放射科医生观察肿块病变的方式一致。本研究使用 DDSM 数据集分别评估了提取的形状特征和边缘特征的有效性。实验结果表明,当使用 Zernike 矩时,圆形肿块在四种形状中最具区分性;四种边缘类型中可以有效地区分边界清晰的肿块。此外,结果还表明,在检索圆形和边界清晰的肿块时,该检索系统在所有肿块病变类型中可以达到最高的精度。