Laboratory of Biology and Medicine of Wild Mammals from Amazonia, Federal University of Pará, Belém, Pará, Brazil.
Anim Reprod Sci. 2010 Dec;122(3-4):276-81. doi: 10.1016/j.anireprosci.2010.09.003. Epub 2010 Sep 15.
The aims of the present study were to: (1) evaluate blood flow in the uterine (UA) and umbilical arteries (Uma) in the pregnant queen, by measuring the resistive index (RI) and pulsatility index (PI); (2) to note the presence or absence of the early diastolic notch and diastolic flow in the UA and Uma flow waveforms, respectively; and (3) perform conceptus echobiometry for fetal growth assessment during pregnancy. Eight healthy pregnant domestic Brazilian Shorthair queens were examined from Days 10 to 50 after mating (mating=Day 0). Triplex Doppler and B-mode ultrasonography were used to assess blood flow and conceptus echobiometry. All pregnancies ended with a normal parturition and birth of live kittens. Prior to parturition, all conceptus dimensions increased significantly, whereas RI and PI peaked between Days 33 and 43 followed by a decrease (P<0.05). The PI least on Day 50. The RI and PI of Uma decreased (P<0.05) during two periods in the fetal development, i.e. from Days 22 to 40 (0.79 ± 0.01 and 1.64 ± 0.04), and from Days 41 to 50 (0.75 ± 0.01 and 1.39 ± 0.05), representing the increased Uma perfusion. Both the complete disappearance of the early diastolic notch in the UA, and the appearance of diastolic flow in the Uma occurred on Day 42 ± 1. It was concluded fetal echobiometry, UA and Uma perfusion, were important end points to assess fetal viability in queens. Furthermore, the current reference values provided a baseline for monitoring normal and abnormal pregnancies in queens.
（1）通过测量阻力指数（RI）和搏动指数（PI）来评估妊娠母猫的子宫（UA）和脐动脉（UMA）的血流；（2）分别记录 UA 和 UMA 血流波形中舒张早期切迹和舒张期血流的存在或缺失；（3）进行胚胎超声生物测量以评估妊娠期间胎儿的生长情况。将 8 只健康的妊娠巴西短毛母猫从交配后第 10 天到第 50 天（交配=第 0 天）进行检查。使用三重多普勒和 B 型超声来评估血流和胚胎超声生物测量。所有妊娠均以正常分娩和活小猫出生结束。在分娩前，所有胚胎尺寸均显著增加，而 RI 和 PI 在第 33 天至第 43 天之间达到峰值，随后下降（P<0.05）。PI 在第 50 天最低。UMA 的 RI 和 PI 在胎儿发育的两个时期下降（P<0.05），即从第 22 天到第 40 天（0.79±0.01 和 1.64±0.04），以及从第 41 天到第 50 天（0.75±0.01 和 1.39±0.05），代表 UMA 灌注增加。UA 中的舒张早期切迹完全消失，UMA 中出现舒张期血流发生在第 42±1 天。结论是，胎儿超声生物测量、UA 和 UMA 灌注是评估母猫胎儿活力的重要终点。此外，目前的参考值为监测母猫正常和异常妊娠提供了基线。
