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一般人群中精神病患者自杀未遂的流行病学。

Epidemiology of suicide attempts among persons with psychotic disorder in the general population.

机构信息

Department of Psychiatry, Helsinki University Central Hospital, National Institute for Health and Welfare, Helsinki, Finland.

出版信息

Schizophr Res. 2010 Dec;124(1-3):22-8. doi: 10.1016/j.schres.2010.09.009. Epub 2010 Oct 8.

Abstract

OBJECTIVE

To establish the epidemiology of suicide attempts in persons with psychotic disorder identified from the general population and to investigate the associations of suicidal behavior with other clinical characteristics and with physical violence against other people.

METHOD

A random sample of 9922 Finnish persons aged 18 years or over was screened for psychotic disorder using multiple sources of information. All screen positives and random sample of screen negatives were invited to an SCID interview. Diagnostic assessment, lifetime history of suicide attempts and violence against others were based on all available systematically evaluated information from the questionnaire, interview and/or case records.

RESULTS

Of persons with a lifetime history of any primary or substance-induced psychotic disorder (n = 264), 34.5% (women: 34.1%, men: 34.9%) had a history of at least one suicide attempt. There were no suicide attempts among persons with delusional disorder, while the rate of suicide attempts was higher among persons with substance-induced psychotic disorders (48.8%) than in persons with other psychotic disorders 41.8%) (χ(2) = 4.4, d.f. = 1, P = 0.036). Suicide attempts were associated with younger age, comorbid substance use disorders, depressive symptoms, and physical violence against other people.

CONCLUSION

Suicide attempts are common in all psychotic disorders except for delusional disorder. They are particularly common in substance-induced psychotic disorder and in persons with comorbid substance use disorders. They are associated with severe depressive symptoms but not with the severity of psychotic symptoms. Suicidal behavior correlates with physical violence against other people.

摘要

目的

从普通人群中确定患有精神病性障碍的个体自杀未遂的流行病学,并调查自杀行为与其他临床特征以及与对他人的身体暴力之间的关系。

方法

使用多种信息来源对 9922 名年龄在 18 岁或以上的芬兰人进行精神病性障碍的随机抽样筛查。所有筛查阳性者和随机抽样的筛查阴性者均被邀请参加 SCID 访谈。诊断评估、自杀未遂和对他人的暴力行为的终生史均基于问卷调查、访谈和/或病例记录中所有可获得的系统评估信息。

结果

在有任何原发性或物质诱发的精神病性障碍(n = 264)的患者中,有 34.5%(女性:34.1%,男性:34.9%)有至少一次自杀未遂史。妄想障碍患者没有自杀未遂,而物质诱发的精神病性障碍患者(48.8%)的自杀未遂率高于其他精神病性障碍患者(41.8%)(χ(2) = 4.4,d.f. = 1,P = 0.036)。自杀未遂与年龄较小、合并物质使用障碍、抑郁症状和对他人的身体暴力有关。

结论

除了妄想障碍外,所有精神病性障碍都有自杀未遂的情况。它们在物质诱发的精神病性障碍和合并物质使用障碍的患者中尤为常见。它们与严重的抑郁症状有关,但与精神病性症状的严重程度无关。自杀行为与对他人的身体暴力有关。

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