Department of Emergency Medicine, Alameda County Medical Center, Highland Hospital, Oakland, CA 94602, USA.
Am J Emerg Med. 2011 Sep;29(7):843.e1-3. doi: 10.1016/j.ajem.2010.07.006. Epub 2010 Oct 8.
Identifying acute pyelonephritis (APN) with early obstructive uropathy is clinically important in the emergency department (ED) because obstructive urolithiasis is an independent risk factor for inpatient death, prolonged hospitalization, and failure of outpatient APN therapy. Furthermore, diagnosis of an early obstructive uropathy can be difficult when based solely on clinical findings. Clinicians may assume the cause of the patient's symptoms to be APN alone, without considering the concurrent presence of an obstructing stone. A feasible screening test to detect early obstructive uropathy in cases of APN has not been previously identified. Plain film radiographs are insensitive in locating a suspected calcified stone. Computed tomography is readily available in most EDs and clearly defines urologic anatomy, but delivers unnecessary ionizing radiation, can prolong ED length of stay, and is not cost-effective as a screening test for all patients diagnosed with APN. We report a case in which a bedside ultrasound identifying hydronephrosis prompted confirmatory computed tomography imaging and emergency consultation of a patient with APN. In this case, hydronephrosis on bedside ultrasound examination was an indirect marker of a distal ureteral obstruction. By detecting the presence of hydronephrosis in patients with APN, emergency physicians may dramatically increase their ability to identify those patients that need further radiographic investigation and ultimately decrease the rate of outpatient treatment failure. Further surveillance data are needed to determine the statistical characteristics of this novel screening test and if routine renal evaluation of all patients with APN is warranted.
在急诊科 (ED) 中,识别伴有早期梗阻性尿路病的急性肾盂肾炎 (APN) 具有重要的临床意义,因为梗阻性尿路结石是住院死亡、住院时间延长和门诊 APN 治疗失败的独立危险因素。此外,仅基于临床发现,诊断早期梗阻性尿路病可能具有挑战性。临床医生可能会认为患者症状的原因仅为 APN,而不考虑同时存在梗阻性结石。以前尚未确定可用于检测 APN 中早期梗阻性尿路病的可行筛选试验。平片对定位可疑钙化结石的敏感性不高。计算机断层扫描在大多数 ED 中均易于获得,可清晰定义泌尿解剖结构,但会带来不必要的电离辐射,延长 ED 住院时间,并且作为所有诊断为 APN 的患者的筛选试验不具有成本效益。我们报告了一例床边超声检查发现肾积水,从而提示进行确认性 CT 成像和 APN 紧急会诊的病例。在这种情况下,床边超声检查中的肾积水是远端输尿管梗阻的间接标志物。通过在患有 APN 的患者中检测到肾积水的存在,急诊医生可能会极大地提高其识别需要进一步放射学检查的患者的能力,并最终降低门诊治疗失败的比率。需要进一步的监测数据来确定这种新的筛选试验的统计学特征,以及是否需要对所有患有 APN 的患者进行常规肾脏评估。