Biomems Research Group, Tecnológico de Monterrey, Campus Monterrey, Monterrey, N.L. 64849, México.
Lab Chip. 2010 Dec 7;10(23):3235-42. doi: 10.1039/c0lc00097c. Epub 2010 Oct 11.
Low frequency alternating current insulator-based dielectrophoresis is a novel technique that allows for highly controlled manipulation of particles. By varying the shape of an AC voltage applied across a microchannel containing an array of insulating cylindrical structures it was possible to concentrate and immobilize microparticles in bands; and then, move the bands of particles to a different location. Mathematical modeling was performed to analyze the distribution of the electric field and electric field gradient as function of the shape of the AC applied potential, employing frequencies in the 0.2-1.25 Hz range. Three different signals were tested: sinusoidal, half sinusoidal and sawtooth. Experimental results demonstrated that this novel dielectrophoretic mode allows highly controlled particle manipulation.
基于低频交流电绝缘体的介电泳是一种新颖的技术，可实现对粒子的高度控制操作。通过改变施加在包含一系列绝缘圆柱形结构的微通道上的交流电压的形状，可以将微粒子集中并固定在带中；然后，将粒子带移动到不同的位置。进行了数学建模以分析电场和电场梯度的分布作为施加的交流电势形状的函数，使用的频率在 0.2-1.25 Hz 范围内。测试了三种不同的信号：正弦波、半正弦波和锯齿波。实验结果表明，这种新颖的介电泳模式允许对粒子进行高度控制的操作。
