Sharan K, Sinha R K
Department of Pediatrics, Nalanda Medical College and Hospital, Patna.
Indian Pediatr. 1990 Dec;27(12):1287-9.
Fine needle aspiration biopsy (FNAB) of spleen was done in 88 suspected cases of Kala-azar. Leishmania donovani (LD) bodies were demonstrated in 56 cases (63.7%) and malarial parasites in 2 (2.3%) while one (1.1%) had picture of chronic myeloid leukemia and another (1.1%) showed acid fast bacilli (AFB) on Ziehl Neelsen staining. Thirty two cases (36.4%), where LD bodies were not found, were subjected to bone marrow examination and none showed LD bodies. There were no complications after FNAB even though 6 patients were having epistaxis. FNAB of spleen is a simple, economical, safe and reliable diagnostic procedure which can be adopted even in remote areas.
对88例疑似黑热病患者进行了脾脏细针穿刺活检。56例(63.7%)发现杜氏利什曼原虫(LD)小体,2例(2.3%)发现疟原虫,1例(1.1%)呈现慢性髓细胞白血病图像,另1例(1.1%)齐-尼氏染色显示抗酸杆菌(AFB)。32例(36.4%)未发现LD小体的患者接受了骨髓检查,均未发现LD小体。尽管有6例患者鼻出血,但细针穿刺活检后未出现并发症。脾脏细针穿刺活检是一种简单、经济、安全且可靠的诊断方法,即使在偏远地区也可采用。