Siddig M, Ghalib H, Shillington D C, Petersen E A
University of Khartoum, Sudan.
Trans R Soc Trop Med Hyg. 1988;82(1):66-8.
Patients with suspected kala-azar had aspirations of spleen, lymph node and bone marrow performed to compare the relative merit of each procedure. Splenic aspiration remains the method most likely to provide microscopic proof of leishmanial infection (18 of 19 samples) and was the only site positive in 5 patients. Lymph node aspirates contained parasites in 20 of 29 patients, whereas bone marrow aspirates provided the diagnosis in 18 of 28. Therefore, lymph node aspiration, with its minimal morbidity, is indicated as the primary diagnostic method in patients in the Sudan with suspected kala-azar. If negative, splenic aspiration should be performed.
疑似黑热病的患者接受了脾脏、淋巴结和骨髓穿刺，以比较每种操作方法的相对优势。脾脏穿刺仍然是最有可能提供利什曼原虫感染微观证据的方法（19个样本中有18个），并且是5例患者中唯一呈阳性的部位。29例患者中有20例淋巴结穿刺液中含有寄生虫，而28例患者中有18例通过骨髓穿刺确诊。因此，鉴于其发病率极低，淋巴结穿刺被指定为苏丹疑似黑热病患者的主要诊断方法。如果结果为阴性，则应进行脾脏穿刺。
