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特殊人群中的高血压:慢性肾脏病、器官移植受者、妊娠、自主神经功能障碍、种族和民族人群。

Hypertension in special populations: chronic kidney disease, organ transplant recipients, pregnancy, autonomic dysfunction, racial and ethnic populations.

机构信息

Department of Medicine, Wayne State University, Detroit Medical Center, MI 48201, USA.

出版信息

Cardiol Clin. 2010 Nov;28(4):623-38. doi: 10.1016/j.ccl.2010.07.007. Epub 2010 Sep 15.

Abstract

The benefits of appropriate blood pressure (BP) control include reductions in proteinuria and possibly a slowing of the progressive loss of kidney function. Overall, medication therapy to lower BP during pregnancy should be used mainly for maternal safety because of the lack of data to support an improvement in fetal outcome. The major goal of hypertension treatment in those with baroreceptor dysfunction is to avoid the precipitous, severe BP elevations that characteristically occur during emotional stimulation. The treatment of hypertension in African Americans optimally consists of comprehensive lifestyle modifications along with pharmacologic treatments, most often with combination, not single-drug, therapy.

摘要

适当控制血压(BP)的好处包括减少蛋白尿,可能减缓肾功能的逐渐丧失。总体而言,由于缺乏支持改善胎儿结局的数据,怀孕期间降低血压的药物治疗主要应用于母亲的安全。在压力感受器功能障碍的患者中,高血压治疗的主要目标是避免情绪刺激时通常发生的急剧、严重的血压升高。非洲裔美国人高血压的最佳治疗方法是综合生活方式改变和药物治疗,大多数情况下是联合治疗,而不是单一药物治疗。

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