Ikeda F, Ohnishi S, Handa S, Iwanaga S, Hosokawa M, Ogawa S, Nakamura Y, Sohma Y, Inoue T
Department of Medicine, Keio University School of Medicine, Tokyo.
J Cardiol. 1990;20(1):159-65.
The severity of aortic regurgitation is difficult to estimate prior to mitral valve replacement (MVR) in cases with tight mitral stenosis (MS), because low output state due to mitral obstruction masks signs of aortic regurgitation. This study clarified left ventricular performance, possibly affected by increased diastolic loading after MVR. The study subjects consisted of 12 patients with pure mitral stenosis (MS group) and 11 with combined mitral stenosis and aortic regurgitation (MSAR group). The diagnosis was made by cardiac catheterization preoperatively. The aortographic grade of aortic regurgitation was class 1 or 2 according to the AHA classification. Both groups were matched in terms of severity in mitral obstruction evaluated by mitral valve area. On preoperative echocardiographic evaluation, there was no difference in the mean values of LVDd, LVSd, and %FS between the groups MS and MSAR. After surgery, symptoms improved in each patient. Echocardiography performed three months after MVR revealed no differences in these parameters between both the groups. We concluded that aortic regurgitation evaluated as class 1 or 2 preoperatively does not increase in respect to left ventricular diastolic overloading and echocardiographic left ventricular performance remains unchanged.
在二尖瓣狭窄(MS)严重的病例中,在二尖瓣置换术(MVR)前很难评估主动脉瓣反流的严重程度,因为二尖瓣梗阻导致的低心输出量状态会掩盖主动脉瓣反流的体征。本研究阐明了左心室功能,其可能受到MVR后舒张期负荷增加的影响。研究对象包括12例单纯二尖瓣狭窄患者(MS组)和11例合并二尖瓣狭窄及主动脉瓣反流患者(MSAR组)。术前通过心导管检查进行诊断。根据美国心脏协会(AHA)分类,主动脉瓣反流的主动脉造影分级为1级或2级。两组在通过二尖瓣面积评估的二尖瓣梗阻严重程度方面相匹配。术前超声心动图评估显示,MS组和MSAR组之间的左心室舒张末期内径(LVDd)、左心室收缩末期内径(LVSd)和左心室短轴缩短率(%FS)平均值无差异。术后,每位患者的症状均有改善。MVR术后三个月进行的超声心动图检查显示,两组之间这些参数无差异。我们得出结论,术前评估为1级或2级的主动脉瓣反流在左心室舒张期超负荷方面不会增加,且超声心动图显示的左心室功能保持不变。