Nishimura S, Nakanishi S, Nishiyama S, Kato K, Nishikawa H, Seki A, Fuse K, Makuuchi H, Konishi T, Kukita M
Division of Cardiology, Toranomon Hospital, Tokyo.
J Cardiol. 1990;20(1):23-30.
The operative mortality and short-term (average 20 months) survival of 100 surgically or medically treated patients, who had coronary artery disease with poor left ventricular function, were examined. One hundred patients with myocardial infarction and radionuclide-documented left ventricular dysfunction (LVEF at rest less than or equal to 40%) were subjects of this study; 85 patients among them underwent simultaneous coronary arteriography. Fifty-six patients whose average age was 59.7 years, and an average LVEF was 30.0%, were treated medically; 44 patients with an average age of 56.0 years, and an average LVEF of 30.9%, were treated surgically, 41 with bypass grafts, two with left ventricular surgery, and one with both these procedures. The medically treated patients consisted of four groups. Group I comprised 15 patients, in whom coronary angiography was contraindicated. Their average age was 67.1 and an average LVEF was 26.2%, Group II, included six patients, who had no indication for surgery because of severely diseased distal coronary arteries. This group had an average age of 57.5 years and an average LVEF of 22.5%. There were one with two-vessel disease and five with three-vessel disease. Group III included five surgical candidates who refused surgery. Their average age and an LVEF were 67.0 and 35.0%, respectively. In this group, there were one with two-vessel disease and four with three-vessel disease. Group IV, comprised 22 patients who did not need surgical therapy. Their average age was 55.3 and average LVEF was 32.5%. They included 22 with one-vessel disease, seven with two-vessel disease and one with three-vessel disease.(ABSTRACT TRUNCATED AT 250 WORDS)
对100例接受手术或药物治疗的冠心病伴左心室功能不全患者的手术死亡率和短期(平均20个月)生存率进行了研究。本研究对象为100例心肌梗死且经放射性核素证实有左心室功能障碍(静息左心室射血分数小于或等于40%)的患者;其中85例患者同时接受了冠状动脉造影。56例平均年龄为59.7岁、平均左心室射血分数为30.0%的患者接受了药物治疗;44例平均年龄为56.0岁、平均左心室射血分数为30.9%的患者接受了手术治疗,41例行搭桥手术,2例行左心室手术,1例行这两种手术。药物治疗的患者分为四组。第一组包括15例患者,冠状动脉造影检查禁忌。他们的平均年龄为67.1岁,平均左心室射血分数为26.2%。第二组包括6例患者,由于冠状动脉远端严重病变而无手术指征。该组平均年龄为57.5岁,平均左心室射血分数为22.5%。其中1例为双支血管病变,5例为三支血管病变。第三组包括5例拒绝手术的手术候选者。他们的平均年龄和左心室射血分数分别为67.0岁和35.0%。该组中,1例为双支血管病变,4例为三支血管病变。第四组包括22例不需要手术治疗的患者。他们的平均年龄为55.3岁,平均左心室射血分数为32.5%。其中包括22例单支血管病变、7例双支血管病变和1例三支血管病变。(摘要截断于250字)