Shimizu Takashi, Masumori Naoya, Hirobe Megumi, Hashimoto Kohei, Maeda Toshihiro, Fukuta Fumimasa, Tanaka Toshiaki, Tsukamoto Taiji
The Department of Urology, Sapporo Medical University.
Hinyokika Kiyo. 2010 Sep;56(9):495-8.
2-Octylcyanoacrylate tissue adhesive (2-OCA ; Dermabond® , Ethicon, Inc., Sommerville, New Jersey) is a synthetic tissue adhesive recently used for skin closure in the treatment of minor lacerations and minor surgical incisions. We have been using this adhesive for wound closure in radical retropubic prostatectomy (RRP) since August 2006. Before that we used a skin stapler. We assessed the effectiveness of the adhesive as a sole dressing after open radical prostatectomy and compared the economic outcomes of 2-OCA and stapled repair. We retrospectively evaluated patients undergoing RRP for whom 2-OCA (101 patients) and a skin stapler (133 patients) were used at our institution. Superficial surgical site infection (SSI) was seen in 3 patients in the glue group and 3 patients in the staple group (p=0.99). Wound dehiscence without SSI was seen in 1 patient in the glue group. The cost of surgery with 2-OCA was much lower than that with the skin stapler. Wound closure using 2-OCA following RRP is acceptable and has benefits in terms of surgical costs.
2-氰基丙烯酸辛酯组织粘合剂（2-OCA；德美邦，爱惜康公司，新泽西州萨默维尔）是一种合成组织粘合剂，最近用于治疗小伤口和小手术切口的皮肤缝合。自2006年8月以来，我们一直在根治性耻骨后前列腺切除术（RRP）中使用这种粘合剂进行伤口闭合。在此之前，我们使用皮肤缝合器。我们评估了该粘合剂作为开放性根治性前列腺切除术后唯一敷料的有效性，并比较了2-OCA和缝合修复的经济结果。我们回顾性评估了在我们机构接受RRP治疗且使用2-OCA（101例患者）和皮肤缝合器（133例患者）的患者。胶水组有3例患者出现浅表手术部位感染（SSI），缝合器组有3例患者出现SSI（p=0.99）。胶水组有1例患者出现无SSI的伤口裂开。使用2-OCA进行手术的成本远低于使用皮肤缝合器的成本。RRP后使用2-OCA进行伤口闭合是可以接受的，并且在手术成本方面有优势。
