Waisberg J, Hamada M, Gonçalves J E, Messias M, Bromberg S H, Jatobá P P, de Godoy A C
Serviço de Gastroenterologia Cirúrgica do Hospital do Servidor Público Estadual Francisco Morato de Oliveira, São Paulo.
Arq Gastroenterol. 1990 Apr-Jun;27(2):53-61.
Twenty-one patients with carcinoid tumors have been analysed. Out of 18 patients the diagnostic was made at operation and out of 3 by autopsy. The most frequent sites of the primary tumors were the appendix (38.1%), ileum (23.8%) and colon (19.9%). Asymptomatic tumors were found incidentally in 10 patients (55.5%). The symptomatic neoplasms were more common in the ileum. No one patients in this series obtained the diagnostic of carcinoid tumors before operation or autopsy. It was not observed the malignant carcinoid syndrome. Sixteen patients (88.8%) were submitted to resection and the mean survival was 10.7 years. Two patients (11.1%) were submitted to palliative operations and the mean survival was 3.5 months. The incidence of metastases in cases with carcinoid greater than 2.0 cm in diameter was 71.4%; on the other hand, the patients with carcinoids 2.0 cm in diameter or smaller than this size disclosed metastases in 7.6%. No patients with appendix carcinoid showed metastases and all patients with metastases presented ileum or colon carcinoids. In this series, the prognostic was related with the lesion's size, the localization of the tumor in the gastrointestinal tract and with the resection or not of the primary neoplasm.
对21例类癌患者进行了分析。18例患者在手术时确诊，3例通过尸检确诊。原发肿瘤最常见的部位是阑尾（38.1%）、回肠（23.8%）和结肠（19.9%）。10例患者（55.5%）偶然发现无症状肿瘤。有症状的肿瘤在回肠中更常见。该系列中没有患者在手术或尸检前被诊断为类癌肿瘤。未观察到恶性类癌综合征。16例患者（88.8%）接受了切除术，平均生存期为10.7年。2例患者（11.1%）接受了姑息性手术，平均生存期为3.5个月。直径大于2.0 cm的类癌患者转移发生率为71.4%；另一方面，直径为2.0 cm或小于此尺寸的类癌患者转移发生率为7.6%。阑尾类癌患者均未出现转移，所有出现转移的患者均为回肠或结肠类癌。在该系列中，预后与病变大小、肿瘤在胃肠道中的定位以及原发肿瘤是否切除有关。
