携带劳氏肉瘤的鸡的淋巴细胞毒性。
Lymphocytotoxicity of chickens bearing Rous sarcomas.
作者信息
McGrail T P, Collins W M, Dunlop W R, Zsigray R M
出版信息
Poult Sci. 1978 Jan;57(1):90-4. doi: 10.3382/ps.0570090.
PMID:209432
Abstract
A 51Cr uptake microcytotoxicity assay was used to determine the cytotoxicity of lymphocytes from chickens bearing Rous sarcomas. Differences in lymphocyte cytotoxicity among individual chickens were statistically significant. Lymphocytes from chickens regressing (or having regressed) their tumors were significantly more cytotoxic than lymphocytes from hosts with progressing tumors. Lymphocytes from chickens with progressing tumors tended to enhance tumor cell growth in vitro.
摘要
采用51Cr摄取微量细胞毒性试验来测定携带劳斯肉瘤的鸡淋巴细胞的细胞毒性。个体鸡之间淋巴细胞细胞毒性的差异具有统计学意义。肿瘤正在消退（或已经消退）的鸡的淋巴细胞的细胞毒性显著高于肿瘤进展期宿主的淋巴细胞。肿瘤进展期鸡的淋巴细胞在体外往往会促进肿瘤细胞生长。
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