Poppenga R H, Trapp A L, Braselton W E, Louden C G, Gumbs J M, Dalley J B
Animal Health Diagnostic Laboratory, Michigan State University, College of Veterinary Medicine, East Lansing 48824.
J Vet Diagn Invest. 1990 Apr;2(2):129-31. doi: 10.1177/104063879000200209.
A litter of 5-week-old Doberman Pinschers with pustular dermatitis was treated dermally with a hexachlorophene-containing emulsion. Shortly after a second treatment, all of the puppies developed neurologic signs consisting of muscle tremors, ataxia, and apparent muscle weakness. The clinical history and signs, histologic lesions within the central nervous system, and measurement of hexachlorophene in liver and kidney tissue confirmed a diagnosis of hexachlorophene toxicosis.
一窝5周大患有脓疱性皮炎的杜宾犬接受了含六氯酚乳液的皮肤治疗。在第二次治疗后不久，所有幼犬都出现了神经症状，包括肌肉震颤、共济失调和明显的肌肉无力。临床病史和体征、中枢神经系统的组织学病变以及肝和肾组织中六氯酚的测量结果证实了六氯酚中毒的诊断。
