一种蜂王浆糖蛋白的鉴定，该糖蛋白带有独特的含有T抗原（Galβ1-3GalNAc）单元的复合型N-聚糖。
Identification of a royal jelly glycoprotein that carries unique complex-type N-glycans harboring the T-antigen (Galβ1-3GalNAc) unit.
作者信息
Kimura Yoshinobu, Nagai Hiromi, Miyamoto Masaki, Kimura Mariko, Yonekura Masami
机构信息
Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan.
出版信息
Biosci Biotechnol Biochem. 2010;74(10):2148-50. doi: 10.1271/bbb.100472. Epub 2010 Oct 7.
In this study, we identified a royal jelly glycoprotein (RJG) that carries a unique complex-type N-glycans harboring the T-antigen (Galβ1-3GalNAc) unit. The amino acid sequence of the tryptic glycopeptide harboring the T-antigen unit was G-E-S-L-X-K (X might be glycosylated Asn), confirmed in the major royal jelly glycoprotein 1 (MRJP1), which is also expressed in the mushroom body of the honeybee brain.
在本研究中，我们鉴定出一种蜂王浆糖蛋白（RJG），其携带一种独特的含有T抗原（Galβ1-3GalNAc）单元的复合型N-聚糖。含有T抗原单元的胰蛋白酶糖肽的氨基酸序列为G-E-S-L-X-K（X可能是糖基化的天冬酰胺），这在主要蜂王浆糖蛋白1（MRJP1）中得到证实，该蛋白也在蜜蜂大脑的蕈形体中表达。
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