Skin Research Laboratory, B. Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
J Invest Dermatol. 2010 Nov;130(11):2535-7. doi: 10.1038/jid.2010.260.
Only indirect evidence supports the concept that a collapse of immune privilege (IP) in hair follicles leads to the development of alopecia areata (AA). In this issue, Kang et al. provide further evidence to support this theory, demonstrating downregulation of the expression of several genes important for the immunosuppressive environment in lesional and perilesional areas of AA.
只有间接证据支持这样一种概念，即毛囊免疫特权（IP）的崩溃导致斑秃（AA）的发展。在本期杂志中，Kang 等人提供了进一步的证据来支持这一理论，表明在 AA 的病变和病变周围区域，几个对免疫抑制环境很重要的基因的表达下调。
