Cogn Neuropsychol. 2000 Feb 1;17(1):117-23. doi: 10.1080/026432900380526.
We present evidence of a striking failure of plasticity in the neural substrates of face recognition, which suggests that the distinction between faces and other objects, and the localisation of faces relative to other objects, is fully determined prior to any postnatal experience. A boy who sustained brain damage at 1 day of age has the classic lesions and behavioural profile of adult-acquired prosopagnosia. He has profoundly impaired face recognition, whereas his recognition of objects is much less impaired. This implies that the human genome contains sufficiently explicit information about faces and nonface objects, or visual features by which they can be distinguished, that experience with these categories is not necessary for their functional delineation and differential brain localisation.
我们提供了一个引人注目的证据，表明在人脸识别的神经基质中存在明显的可塑性失败，这表明在任何产后经验之前，就已经完全确定了面孔和其他物体之间的区别，以及相对于其他物体的面部定位。一名在 1 天大时遭受脑损伤的男孩具有成人获得性面孔失认症的典型病变和行为特征。他的人脸识别能力严重受损，而他对物体的识别能力受损则要小得多。这意味着人类基因组包含了足够明确的关于面孔和非面孔物体的信息，或者是可以区分它们的视觉特征，因此这些类别的经验对于它们的功能划分和大脑的差异定位并不是必需的。
