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大段异体骨并带髓内腓骨移植在胫骨恶性肿瘤切除后间插式重建中的应用。

The use of massive allograft with intramedullary fibular graft for intercalary reconstruction after resection of tibial malignancy.

机构信息

Department of Orthopaedic Oncology, Xi Jing Hospital Affiliated to the Fourth Military Medical University, Xi'an, People's Republic of China.

出版信息

J Reconstr Microsurg. 2011 Jan;27(1):37-46. doi: 10.1055/s-0030-1267381. Epub 2010 Oct 13.

Abstract

Reconstruction after intercalary excision of tibia malignancy is challenging. The combined use of a vascularized fibular flap and allograft can provide a reliable reconstructive option. Eight patients underwent reconstruction with an allograft and vascularized fibula following tibia malignancy resection. Patients were examined clinically and radiographically. The average age of patients was 16.5 years. The mean follow-up time was 38.4 months. Contralateral free fibula flap was used in three patients and ipsilateral pedicle fibula in five. The average length of defect was 11.8 cm and of fibula flap was 15.9 cm. Primary union was achieved in seven patients. The average time for bone union was 5.8 months at fibula-tibia junction and 14.1 months at allograft-tibia junction. Five patients had 10 complications. The Musculoskeletal Tumor Society average score was 90.8% at final follow-up. Intramedullary fibular flap in combination with massive allografts provide an excellent option for reconstruction of large bony defects after tibial malignancy extirpation. Ipsilateral pedicle fibula transportation had the advantages of short operation time and avoidance of donor site complications compared with the contralateral free fibula transfer.

摘要

胫骨恶性肿瘤切除后进行节段性切除的重建具有挑战性。带血管腓骨瓣和同种异体骨的联合应用可为可靠的重建选择提供依据。8 例胫骨恶性肿瘤切除术后患者采用同种异体骨和带血管腓骨进行重建。对患者进行了临床和影像学检查。患者平均年龄为 16.5 岁。平均随访时间为 38.4 个月。3 例患者采用对侧游离腓骨瓣,5 例患者采用同侧带蒂腓骨瓣。缺损的平均长度为 11.8cm,腓骨瓣的平均长度为 15.9cm。7 例患者达到了一期愈合。腓骨-胫骨交界处的骨愈合平均时间为 5.8 个月,同种异体骨-胫骨交界处的骨愈合平均时间为 14.1 个月。5 例患者发生了 10 种并发症。在最终随访时,肌肉骨骼肿瘤学会的平均评分为 90.8%。带髓内腓骨瓣和大段同种异体骨联合应用为胫骨恶性肿瘤切除后重建大骨缺损提供了极好的选择。与对侧游离腓骨移植相比,同侧带蒂腓骨移植具有手术时间短和避免供区并发症的优点。

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