Division of Hospital Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Hosp Med. 2010 Oct;5(8):460-5. doi: 10.1002/jhm.779.
Unplanned (unexpected) transfers to the intensive care unit (ICU) are typically preceded by physiologic instability. However, trends toward instability may be subtle and not accurately reflected by changes in vital signs. The shock index (SI) (heart rate/systolic blood pressure as an indicator of left ventricular function, reference value of 0.54) may be a simple alternative means to predict clinical deterioration.
To assess the association of the SI with unplanned ICU transfers.
Retrospective case-control study.
Academic medical center.
Fifty consecutive general medical patients with unplanned ICU transfers between 2003 and 2004 and 50 matched controls admitted to the same general medical unit between 2002 and 2004.
Demographic data and vital signs abstracted from chart review.
The SI was associated with unplanned ICU transfer at values of 0.85 or greater (P < 0.02; odds ratio, 3.0) and there was a significant difference between the median of worst shock indices of cases and controls (0.87 vs. 0.72; P < 0.005). There was no significant difference in age, race, admission ward, or Charlson Comorbidity Index, but hospital stay for cases was significantly longer (mean [standard deviation, SD], 14.8 [9.7] days vs. 5.7 [6.3] days; P < 0.001).
SI is associated with unplanned transfers to the ICU from general medical units at values of 0.85 or greater. Future studies will determine whether SI is more accurate than simple vital signs as an indicator of clinical decline. If so, it may be a useful trigger to activate medical emergency or rapid response teams (RRTs).
非计划性(意外)转入重症监护病房(ICU)通常先于生理不稳定。然而,不稳定的趋势可能很微妙,不能准确反映在生命体征的变化上。休克指数(SI)(心率/收缩压作为左心室功能的指标,参考值为 0.54)可能是一种简单的替代方法来预测临床恶化。
评估 SI 与非计划性 ICU 转科的关系。
回顾性病例对照研究。
学术医疗中心。
2003 年至 2004 年间连续 50 例非计划性 ICU 转科的普通内科患者和 2002 年至 2004 年间同一普通内科病房收治的 50 例匹配对照。
从图表回顾中提取人口统计学数据和生命体征。
SI 与非计划性 ICU 转科相关,值为 0.85 或更高(P<0.02;优势比,3.0),且病例和对照组最差休克指数中位数之间存在显著差异(0.87 对 0.72;P<0.005)。年龄、种族、入院病房或 Charlson 合并症指数无显著差异,但病例的住院时间明显更长(平均值[标准差,SD],14.8[9.7]天对 5.7[6.3]天;P<0.001)。
SI 在值为 0.85 或更高时与普通内科病房非计划性转入 ICU 相关。未来的研究将确定 SI 是否比简单的生命体征更准确地作为临床恶化的指标。如果是这样,它可能是激活医疗急救或快速反应小组(RRT)的有用触发因素。